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[ACIE] Prof. Haichao Xu published a paper entitled "Electrochemical Synthesis of Imidazo-Fused N-Heteroaromatics via C-N Bond Forming Radical Cascade"

2017-12-27

Title: Electrochemical Synthesis of Imidazo-Fused N-Heteroaromatics via C-N Bond Forming Radical Cascade

Author: Zhong-Wei Hou, Zhong-Yi Mao, Yared Yohannes Melcamu, Xin Lu, Hai-Chao Xu

Abstract:

We have developed a unified strategy for preparing a variety of imidazo-fused N-heteroaromatics through regiospecific electrochemical (3+2) annulation reaction of heteroarylamines with tethered internal alkynes. The electrosynthesis employs a novel tetraarylhydrazine as the catalyst, has a broad substrate scope, and obviates the need for transition-metal catalysts and oxidizing reagents.

Full-Link: http://onlinelibrary.wiley.com/doi/10.1002/anie.201711876/full